Status:

COMPLETED

Appropriate Inhaler Use of Tiotropium As Add-on Therapy in Symptomatic Asthma

Lead Sponsor:

Chang Gung Memorial Hospital

Conditions:

Asthma

Eligibility:

All Genders

20-75 years

Phase:

NA

Brief Summary

This pragmatic, two-arm, randomized controlled trial study aim to survey the inhaler errors of add-on tiotropium therapy with ICS+LABA in real-world practice of asthma patients and the efficacy of rec...

Detailed Description

1. The clinical efficacy of tiotropium as add-on treatment to ICS with a LABA have been demonstrated in clinical trials in adult patients with symptomatic asthma. 2. Certain patients of daily care, li...

Eligibility Criteria

Inclusion

  • Age 20 to 75 years old asthmatic patients under regular treatment
  • Received medium to high dose ICS with LABA at least 3 months
  • Persistent asthma related symptoms: asthma control questionnaire (ACQ-7\>1.5)
  • Physicians in charged prescribed Tiotropium as add-on therapy according to clinical judgement.

Exclusion

  • Refuse to provide inform consent
  • Pregnancy or breastfeeding women
  • Patients with chronic obstructive pulmonary disease
  • Using other Long-acting Muscarinic Antagonists e.g. Sebree, Ultibro, Anoro and Spiolto

Key Trial Info

Start Date :

March 4 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 20 2023

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT04696965

Start Date

March 4 2021

End Date

November 20 2023

Last Update

February 28 2025

Active Locations (1)

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Department of Thoracic Medicine, Chang Gung Memorial Hospital

Taoyuan District, Taiwan, 33305