Status:
COMPLETED
Helicobacter Pylori Eradication in Functional Dyspepsia
Lead Sponsor:
Sir Ganga Ram Hospital
Conditions:
Dyspepsia
Helicobacter Pylori Infection
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study is designed to study benefit of eradicating Helicobacter Pylori in patients with functional dyspepsia as compared to symptomatic treatment only. Helicobacter pylori positive patients with F...
Detailed Description
Functional dyspepsia (FD), is a common problem with many associations. About 50% of the patients with FD have coexistent Helicobacter pylori (HP) associated gastritis. Many investigators have tried t...
Eligibility Criteria
Inclusion
- Age \> 18 years
- Patients fulfilling the ROME-IV criteria of Functional Dyspepsia
- Signed informed consent.
Exclusion
- Pregnant and lactating females
- Patients with predominant symptoms of heartburn or irritable bowel syndrome; alarm symptoms; history of peptic ulcer, upper gastrointestinal tract surgery, or biliary colic
- Previous treatment for eradication of H pylori.
- Known allergies to study medication or alcohol or drug abuse.
- Use of antibiotics or bismuth during the 4 weeks before enrolment, proton pump inhibitors during the 2 weeks before enrolment, or treatment with histamine-2 receptor blockers in the week before enrolment will not be permitted.
- Patients unable to answer the study questionnaires.
- Patients unwilling or unable to provide consent.
- Patient on HIV/AIDS medications, blood thinners, clopidogrel, cyclosporine, digoxin, iron supplements, fluconazole or ketoconazole, probenecid, rifabutin, sildenafil, tacrolimus, theophylline, sulfa drugs, cholesterol-lowering medicines, heart rhythm medications, sedatives, seizure medications, or tetracycline antibiotics.
Key Trial Info
Start Date :
September 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2019
Estimated Enrollment :
202 Patients enrolled
Trial Details
Trial ID
NCT04697641
Start Date
September 1 2017
End Date
May 31 2019
Last Update
January 14 2021
Active Locations (1)
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1
Department of Gastroenterology & Hepatology, Sir Ganga Ram Hospital
New Delhi, India, 110060