Status:
COMPLETED
Topical Tranexamic Acid Versus Topical Vitamin C With Microneedling in Periorbital Hyperpigmentation; Comparative Study
Lead Sponsor:
Kasr El Aini Hospital
Conditions:
Periorbital Hyperpigmentation
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Both vitamin C 20% and tranexamic acid 5mg/ml combined with microneedling were used for treatment of periorbital hyperpigmentation in a comparative pattern and both resulted in significant improvement...
Detailed Description
Sixty patients with periorbital hyperpigmentation were enrolled, patients were divided into 2 groups; 30 each. clinical grading according to sheth et al.,2014 , dermoscopic evaluation, visual analogue...
Eligibility Criteria
Inclusion
- both genders.
- age ≥ 18 years.
- pigmentary, vascular and mixed types of dark halos
Exclusion
- pregnancy and lactation
- patients who received treatment in the past 3 months
- patients with active dermatologic diseases or history of atopic dermatitis.
- history of allergy to tranexamic acid or vitamin c
- history of keloid or hypertrophic scars
- pure structural type of dark halos, pigmentary demarcation lines
Key Trial Info
Start Date :
November 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 15 2020
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04697992
Start Date
November 1 2019
End Date
March 15 2020
Last Update
January 6 2021
Active Locations (1)
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1
Doaa Mohsen
Giza, Egypt