Status:

COMPLETED

Comparative Study Between Valproate and Memantine in the Prophylactic Management of Episodic Migraine.

Lead Sponsor:

Universidad Autonoma de San Luis Potosí

Conditions:

Migraine Headache

Eligibility:

All Genders

18-65 years

Phase:

PHASE3

Brief Summary

Migraine is one of the three most disabling diseases worldwide. Constituted by recurrent episodes of headache, characterized by unilateral location, throbbing character, moderate or severe intensity, ...

Detailed Description

Migraine is a primary headache, currently one of the three most disabling diseases globally. It has an annual and lifetime prevalence of 18% and 33% in women, and 6 to 13% in men, respectively, with a...

Eligibility Criteria

Inclusion

  • Men and women from 18 to 65 years old.
  • Diagnosis of migraine according to the ICHD-III of the IHS at least one year before the study.
  • You must have at least 4-14 migraine attacks per month.
  • Not receiving prophylactic treatment for migraine
  • Sign informed consent

Exclusion

  • Pregnant or lactating patients.
  • Patients with another type of non-migraine headache.
  • Allergy to Sodium Valproate and/or Memantine
  • Being a carrier of systemic disease (infectious, immunological, or metabolic processes) or cardiovascular (myocardial, coronary, or valvular disease) prevents their participation in the study.

Key Trial Info

Start Date :

February 15 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 15 2020

Estimated Enrollment :

33 Patients enrolled

Trial Details

Trial ID

NCT04698525

Start Date

February 15 2019

End Date

January 15 2020

Last Update

May 9 2024

Active Locations (1)

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1

Hospital Central Dr. Ignacio Morones Prieto

San Luis Potosí City, Mexico, 78290