Status:

SUSPENDED

Magnetic Resonance Imaging (MRI) to Predict Outcomes of Pancreatic Ductal Adenocarcinoma (PDAC)

Lead Sponsor:

Cedars-Sinai Medical Center

Conditions:

PDAC - Pancreatic Ductal Adenocarcinoma

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to assess if Six-Dimensional Magnetic Resonance Imaging (6D-MRI) is effective in predicting outcomes in patients with pancreatic ductal adenocarcinoma (PDAC).

Detailed Description

The overarching goal of this pilot study is to evaluate the usefulness of a novel Magnetic Resonance Imaging (MRI) approach, which measure properties of tumor microenvironment (i.e. vascularity, fibro...

Eligibility Criteria

Inclusion

  • Pancreatic cancer patients (with resectable or borderline resectable or locally advanced tumors) who will undergo neoadjuvant chemotherapy
  • Patients able to undergo at least two sets of MRI sessions

Exclusion

  • Patients who have previously been treated for PDAC
  • Patients unable to undergo MRI exam w/contrast
  • Patients with metastatic pancreatic cancer visualized on index diagnostic imaging
  • Patients with certain metallic implants
  • Patients experiencing claustrophobia
  • Persons with allergy to animal dander or animal-instigated asthma

Key Trial Info

Start Date :

May 19 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2026

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT04700488

Start Date

May 19 2022

End Date

January 1 2026

Last Update

December 17 2025

Active Locations (1)

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1

Cedars-Sinai Medical Center

Los Angeles, California, United States, 90048