Status:

UNKNOWN

Diffusion-weighted MRI to Predict Treatment Response in Stereotactic Radiotherapy of Central Nervous System (CNS) Metastases

Lead Sponsor:

Lund University Hospital

Conditions:

Radiotherapy

Brain Metastases

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Stereotactic radiation therapy is an important and common method of treating brain metastases in patients with malignant disease. Today, however, there are no methods available to determine the metast...

Eligibility Criteria

Inclusion

  • Patients prescribed stereotactic radiation therapy to the brain, where MRI imaging is included in the treatment preparations.
  • Cohesive remaining solid tumor component of ≥10mm.
  • Age ≥18 years.
  • World Health Organisation (WHO) performance status 0-1.

Exclusion

  • Inability to decide for oneself on participation in the study.
  • Inability to understand the Swedish language.
  • Metastases close to the base of the skull.
  • Contraindications to conducting an MRI examination.
  • Contraindications to obtaining contrast media during MRI examination.
  • Expected survival less than 6 months.
  • Previous radiation treatment to the same site in the brain, i.e. current treatment is a rope radiation.
  • \-

Key Trial Info

Start Date :

December 28 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2023

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT04700748

Start Date

December 28 2020

End Date

December 31 2023

Last Update

January 8 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Lund University Hospital

Lund, Sweden, 221 85

Diffusion-weighted MRI to Predict Treatment Response in Stereotactic Radiotherapy of Central Nervous System (CNS) Metastases | DecenTrialz