Status:
COMPLETED
Walking Pattern Characteristics in Normal Pressure Hydrocephalus
Lead Sponsor:
University of Zurich
Collaborating Sponsors:
ETH Zurich
Conditions:
Idiopathic Normal Pressure Hydrocephalus (INPH)
Eligibility:
All Genders
18-100 years
Phase:
NA
Brief Summary
20 patients who are diagnosed with NPH receive a set of 5 wearable gyroscopes (IMUs, ZurichMove sensors) for a period of 3 days for measurement and characterization of their walking in an ambulatory s...
Detailed Description
Temporary attachment of IMUs to wrists and ankles of the patients and probands for a period of three days and recording of movement during a 10 meter-walking test, 180° turnaround and during normal mo...
Eligibility Criteria
Inclusion
- Age limits for the NPH patient group and the matched healthy vonunteers group are 60-100 years.
- Age limits for the young healthy volunteers group are 18-40 years.
- NPH patient group:
- Informed Consent as documented by signature prior to any study related procedures or informed consent by a legal representative in case of cognitive deficits.
- Male and female patients alike
- Age between 60 and 100 years
- Clinical suspect for NPH
- Significant improvement (by more than 10%) in walking speed or endurance in a standardized CSF-TAP test (of at least 35 ml CSF).
- Planned implantation of a VP shunt for NPH treatment (independently from the study).
- Matched controls group:
- Informed Consent as documented by signature prior to any study related procedures
- Male and female patients alike (matched to group 1)
- Age between 60 and 100 years (matched to group 1)
- No clinical suspect for NPH or any other movement disorder
- Young controls group:
- Informed Consent as documented by signature prior to any study related procedures
- Male and female patients alike (matched to group 1)
- Age between 18 and 40 years
- No clinical suspect for NPH or any other movement disorder
Exclusion
- Enrolment of the investigator, his/her family members, employees and other dependent persons (only for patients; no exclusion criteria for controls),
- Apparent or suspected movement disorder or other known disorder, which might affect normal standing or walking
- Cardiovascular disorders, which might affect physical resilience
- Pregnant women
- Pre-menopausal state of female patients and probands in groups 1 and 2.
- Children and adolescents
Key Trial Info
Start Date :
January 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 25 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04702035
Start Date
January 1 2018
End Date
April 25 2024
Last Update
April 26 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Dept. of Neurosurgery, Zurich University Hospital
Zurich, Switzerland, 8091