Status:

TERMINATED

Value of Functional Magnetic Resonance Imaging of Hepatocellular Carcinoma After Transarterial Chemoembolization or Transarterial Radioembolization

Lead Sponsor:

University of Zurich

Collaborating Sponsors:

Centre Hospitalier Universitaire Vaudois

Conditions:

Liver Neoplasm

Eligibility:

All Genders

18+ years

Brief Summary

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide and is commonly treated with transarterial locoregional therapies (transarterial chemoembolization (TACE) or transarteri...

Eligibility Criteria

Inclusion

  • Informed Consent as documented by signature (Appendix Informed Consent Form)
  • Male and Female patients ≥18 years of age
  • Patients with HCC according to imaging findings and/or histology and scheduled for TACE or TARE

Exclusion

  • Women who are pregnant or breast feeding,
  • Please note that female participants who are surgically sterilised / hysterectomised or post-menopausal for longer than 2 years are not considered as being of child bearing potential.
  • Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant,
  • Previous enrolment into the current study,
  • Patients with impaired renal function (estimated glomerular filtration rate \<30 ml/min)
  • Patients with non-MRI compatible metallic or electronic implants, devices or metallic foreign bodies (cardiac pacemaker, shrapnel, cochlea implants, neurostimulator, or other non-MRI compatible implants).
  • Tumor-directed therapy (i.e. systemic chemotherapy) between transarterial therapy and 3-months follow-up MRI exam

Key Trial Info

Start Date :

September 11 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 30 2019

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT04702230

Start Date

September 11 2017

End Date

April 30 2019

Last Update

January 8 2021

Active Locations (1)

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1

University Hospital Zurich

Zurich, Switzerland