Status:
COMPLETED
Hyaluronic Acid for Residual Periodontal Pockets Adjunctive Treatment
Lead Sponsor:
University of Roma La Sapienza
Collaborating Sponsors:
University of Rijeka
University of Zagreb
Conditions:
Periodontitis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Objective: To evaluate the adjunctive effect of hyaluronic acid (HA) gel in the treatment of residual periodontal pockets over a 12-month period. Materials and Methods: Periodontal patients enrolled ...
Detailed Description
Population A total of 144 patients were enrolled from 6 university clinical centers (Sapienza University of Rome, Department of Periodontology, Rome, Italy ; University of Rijeka, School of Dental Med...
Eligibility Criteria
Inclusion
- at least 18 years of age
- systemically healthy,
- smoking less than 10 cigarettes/day
- having been treated for periodontitis but with at least one single residual pocket of 5-9mm of depth located in the anterior area (incisors and canines)
- full-mouth bleeding score (FMBS)
- full-mouth plaque score (FMPS) less than 20%
- showing a good compliance to oral hygiene instructions
Exclusion
- were pregnancy/lactation
- use of antibiotics in the last 3 months for a period of two weeks or more
- use of drugs causing gingival hyperplasia
- use of corticosteroids or anti-inflammatory drugs for a period of two weeks or more
- presence of diseases knowing to influence the wound healing/tissue response
- thyroid or pituitary gland malfunction or abnormal hormonal levels
- hyaluronic acid contraindications
- subjects under anticoagulant treatment
- use of systematic antibiotics for endocarditis prophylaxis
- radiation therapy in head and neck area
- use of bisphosphonate drugs prescribed for patients with osteoarthritis
- tooth mobility.
Key Trial Info
Start Date :
January 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2018
Estimated Enrollment :
144 Patients enrolled
Trial Details
Trial ID
NCT04702334
Start Date
January 1 2016
End Date
November 1 2018
Last Update
January 8 2021
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