Status:

COMPLETED

TRANSFORM-HF Ancillary Mechanistic Study

Lead Sponsor:

Inova Health Care Services

Collaborating Sponsors:

National Institutes of Health (NIH)

Duke University

Conditions:

Heart Failure

Eligibility:

All Genders

18+ years

Brief Summary

Patients with heart failure are frequently treated with diuretics, including furosemide and torsemide, but it is not known if one is better than the other. The TRANSFORM-HF trial is studying if torsem...

Detailed Description

Patients who are enrolling in the TRANSFORM-HF study or being prescribed Torsemide or Furosemide at hospital discharge will provide blood and urine at the time of study enrollment (within 72 hours of ...

Eligibility Criteria

Inclusion

  • Participation in the TRANSFORM-HF trial or prescription of Torsemide or Furosemide
  • Willing to provide blood and urine sample at enrollment and follow-up

Exclusion

  • Inability or unwillingness to comply with the study requirements

Key Trial Info

Start Date :

December 10 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 30 2023

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT04702958

Start Date

December 10 2020

End Date

May 30 2023

Last Update

October 10 2023

Active Locations (9)

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Page 1 of 3 (9 locations)

1

Yale University School of Medicine

New Haven, Connecticut, United States, 06510

2

Ochsner Clinic Foundation

New Orleans, Louisiana, United States, 70121

3

Baltimore VA

Baltimore, Maryland, United States, 21201

4

University of Minnesota

Minneapolis, Minnesota, United States, 55455