Status:

COMPLETED

Comparison of Water Sorption Capacity and the Composition of Bronchial Fluids of Healthy Persons and Patients With Chronic Obstructive Bronchitis (COPD)

Lead Sponsor:

Georg Nilius, Prof DR med

Conditions:

COPD

Healthy

Eligibility:

All Genders

18+ years

Brief Summary

Pilot basic research study on the properties of bronchial mucus. Examination of the sorption and desorption properties, mucin concentration, and structure of the mucus from healthy airways compared to...

Detailed Description

Mucus, of the correct composition, maintains airway hydration and protects the airway from inhaled particles through mucociliary transport. In chronic inflammatory airway diseases such as COPD or cyst...

Eligibility Criteria

Inclusion

  • Age\>18
  • COPD or other disease requiring bronchoscopy or elective surgery
  • Signed informed consent form

Exclusion

  • Not able to consent
  • Linguistic, cognitive, or other obstacles

Key Trial Info

Start Date :

July 9 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 17 2023

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT04703023

Start Date

July 9 2020

End Date

May 17 2023

Last Update

May 22 2023

Active Locations (1)

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1

Kliniken Essen-Mitte, Evang. Huyssens-Stiftung/Knappschaft gGmbH

Essen, North Rhine-Westphalia, Germany, 45276