Status:
UNKNOWN
Lens Extraction Combined With Goniosynechialysis Versus Trabeculectomy
Lead Sponsor:
Eye & ENT Hospital of Fudan University
Conditions:
Glaucoma, Angle-Closure
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
To compare the effectiveness of lens extraction combined with goniosynechialysis and trabeculectomy in treating advanced angle-closure glaucoma.
Detailed Description
Advanced angle closure glaucoma (AACG) can result in severe visual function defect or even blindness with or without acute attacks. Different from open angle glaucoma (OAG), the main principle of trea...
Eligibility Criteria
Inclusion
- Age between 40 years old to 80 years old
- more than 180-degree synechial closure of anterior chamber angle on gonioscopy
- IOP higher than 21mmHg under the use of more than two anti-glaucoma eye drops
- mean deviation of visual field worse than -12dB on Humphrey 24-2
- phakic eyes
Exclusion
- Snellen visual acuity worse than 0.02
- history of ocular trauma
- uveitis
- previous ocular surgeries
- significant conjunctival scar
- visible neovascular on iris or anterior chamber angle
- other severe eye diseases that would affect visual function significantly, such as age-related macular degeneration and pathogenic myopia.
Key Trial Info
Start Date :
January 30 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
316 Patients enrolled
Trial Details
Trial ID
NCT04703712
Start Date
January 30 2021
End Date
December 1 2024
Last Update
March 1 2023
Active Locations (1)
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1
Eye & ENT Hospital
Shanghai, China, 200031