Status:
COMPLETED
Pregabalin vs. Gabapentin on Reducing Opioid Usage
Lead Sponsor:
CAMC Health System
Collaborating Sponsors:
West Virginia Clinical and Translational Science Institute
Conditions:
Analgesics
Gabapentin
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This is a single-center, randomized, open-label, Phase 4 clinical trial investigating the efficacy of multiple-dose administrations of Pregabalin or Gabapentin in combination with traditional opioid p...
Detailed Description
Patients included in this trial were admitted under the care of the Trauma Nurse Practitioners (TNPs) who lead management of these patients. The TNP service is a 24/7 model where TNPs admit and manage...
Eligibility Criteria
Inclusion
- Nurse Practitioner service admissions
- 18 years of age or older
- Patients enrolled within 36 hours of admission
- Anticipated duration of hospitalization \> 24 hours from time of consent
- Active order(s) for opioids in place at the time of enrollment
Exclusion
- Clinician discretion based on patient care management
- Intubated patients
- Patients with epidural
- Patients with pregabalin/gabapentin as home medications
- Patients receiving pregabalin/gabapentin upon admission
- Traumatic brain injury patients
- CrCl\<30ml/min or on HD
- Unable to take enteral medications
- On Patient Controlled Analgesia (PCA)
- Patients with complicated wound closure
- History of epilepsy
- Documented history of substance use disorder
Key Trial Info
Start Date :
April 12 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 13 2024
Estimated Enrollment :
109 Patients enrolled
Trial Details
Trial ID
NCT04705480
Start Date
April 12 2021
End Date
December 13 2024
Last Update
January 6 2026
Active Locations (1)
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1
Charleston Area Medical Center"s Level 1 Trauma Center
Charleston, West Virginia, United States, 25301