Status:
COMPLETED
Efficacy of Oral Supplementation of Probiotics in Children With Atopic Dermatitis
Lead Sponsor:
B.P. Koirala Institute of Health Sciences
Collaborating Sponsors:
Nepal Health Research Council
Conditions:
Atopic Dermatitis
Eligibility:
All Genders
4-17 years
Phase:
NA
Brief Summary
Various clinical studies have evaluated the role of probiotics in children with atopic dermatitis, with some studies showing improvement in clinical outcome after supplementation of probiotics and oth...
Detailed Description
Atopic dermatitis (AD) is the common chronic inflammatory skin disease with relapsing courses that often start in infancy and childhood. It is characterized by erythema, itchy papules, occasionally ve...
Eligibility Criteria
Inclusion
- Children with a diagnosis of atopic dermatitis that meet Hanifin and Rajka criteria
- SCORAD ( SCORing Atopic Dermatitis) index 15- 50 at the time of enrollment
Exclusion
- SCORAD (SCORing Atopic Dermatitis) index \<15 or \>50.
- Children treated with systemic corticosteroids, methotrexate, or cyclosporine in the previous 3 months and antibiotics in the previous 2 weeks.
- Immunocompromised children.
- Concomitant diagnosis of intolerance to gluten and/ or lactose.
- Pre-existing hypersensitivity to components contained in the probiotics.
- Children suffering from chronic infectious diseases.
- A child with other known systemic diseases (heart, liver or kidney diseases).
- Known case of short gut syndrome.
- Refusal of children's parents to participate in the study.
Key Trial Info
Start Date :
January 3 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 15 2021
Estimated Enrollment :
98 Patients enrolled
Trial Details
Trial ID
NCT04706559
Start Date
January 3 2021
End Date
December 15 2021
Last Update
December 16 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
B.P. Koirala Institute of Health Sciences
Dharān, Nepal, 7053