Status:
ACTIVE_NOT_RECRUITING
Implant Supported Single Crowns With Different Retention Modes
Lead Sponsor:
Medical University of Graz
Conditions:
Complications: Inflammatory Reactions, Mechanical Complications
Eligibility:
All Genders
18-99 years
Phase:
NA
Brief Summary
This study aims to examine the inflammatory response mediated by MMP-8 (Matrix metalloproteinase-8 ) level in peri-implant sulcus fluid adjacent to screw-retained, cemented or using the Acuris-system ...
Detailed Description
After giving their written consent volunteers will be screened and eligible subjects will be randomized to three different groups. In group 1 Acuris® is used as fixation type; in group 2 screw retenti...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- capability of giving an informed consent
- good health as defined by the subjects medical history (no contraindications as described in the exclusion criteria below)
- age 18 to 99 years
- Good periodontal status: BOP \< 20%, PI \< 30%, no PD \> 4mm
- No heavy smokers (\< 10 cigarettes/day)
- at least 1 missing tooth in the premolar and molar region (with at least a mesial neighboring tooth/implant showing adequate hard- and soft tissue situation without the need of crestal hard- or soft tissue augmentation) either in the maxilla or in the mandible requiring implant therapy for reconstruction, requiring sinus floor augmentation or not.
- Exclusion Criteria
- Insufficient bone volume for implant placement requiring GBR (guided bone regeneration) procedure in crestal area.
- Heavy Smokers (\>10 cigarettes/day)
- Medication with a contraindication for implant therapy (especially antiresorptive therapy, ongoing or recently completed local radiotherapy, systematic diseases, ongoing immunosuppressive therapy, functional disorders like Bruxism).
- Skeletal immaturity.
- Any active malignancy or ongoing treatment for malignancy.
- An active infection (e.g. caries, gingivitis, periodontitis) at or in the neighboring area of the operative site.
- Pregnancy
- unable or unwilling to return for follow-up visits for a period of at least 16 months
Exclusion
Key Trial Info
Start Date :
March 4 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2025
Estimated Enrollment :
39 Patients enrolled
Trial Details
Trial ID
NCT04707716
Start Date
March 4 2021
End Date
November 1 2025
Last Update
November 20 2024
Active Locations (1)
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1
Medical University of Graz, Department of Dental Medicine and Oral Health, Division of Oral Surgery and Orthodontics
Graz, Austria, 8010