Status:
UNKNOWN
Antiviral T Lymphocyte Immunity During Acute COVID-19 Infection
Lead Sponsor:
University Hospital, Rouen
Conditions:
Corona Virus Infection
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The SARS-CoV-2 (COVID-19) infection is causing a global pandemic and a major health crisis in France. Immunity is the body's ability to defend itself against infectious agents such as viruses. The pr...
Eligibility Criteria
Inclusion
- Patient with an acute SARS-CoV-2 infection, confirmed by PCR or typical CT images, requiring hospitalization in a COVID unit at the Rouen University Hospital (pneumonic form requiring oxygen therapy \< 4 L/min.)
- Rouen University Hospital staff free of any symptomatology compatible with an SARS-CoV-2 infection (fever, cough, fatigue, loss of taste, loss of smell) since February 1, 2020
- Age ≥ 18 years old
- Adult patient who has read and understood the information letter and signed the consent form
- Affiliation to a social security scheme
Exclusion
- Patient with PCR-confirmed SARS-CoV-2 infection and hospitalized in intensive care units (acute respiratory distress and/or organ failure, whose pathogenesis may differ from the more frequently described forms with secondary aggravation (5)).
- Patient with PCR-confirmed but non-hospitalized SARS-CoV-2 infection (non-acute form, managed by confinement)
- A person participating in a therapeutic trial that may interfere with the procedures being investigated, including lymphocyte response prior to D+56±14 days.
- Known Pregnancy
- Person deprived of liberty by an administrative or judicial decision or person placed under judicial protection / subtutorship or guardianship
- Staff at the Rouen University Hospital with SARS-CoV-2 infection confirmed by PCR and/or typical scan images during the epidemic period.
- Hospital staff who were exposed to the virus (working in a Covid unit)
Key Trial Info
Start Date :
April 16 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 10 2021
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04707820
Start Date
April 16 2020
End Date
June 10 2021
Last Update
January 13 2021
Active Locations (1)
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1
Rouen University Hospital
Rouen, France