Status:
UNKNOWN
Effects of Aerobic Exercise Modulation on Brain Physiology and Cognition in Young Adults With Depression
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Depression
Eligibility:
All Genders
20-35 years
Phase:
NA
Brief Summary
Major depressive depression (MDD) affects a quarter of young adults and is associated with marked global burden in this population. Recently, growing literature has shown that cognitive dysfunction is...
Detailed Description
The study are interested in the physiological foundation of the impact of aerobic exercise on cognitive performance in youth MDD subjects. Combined application of neurophysiological intervention and r...
Eligibility Criteria
Inclusion
- Inclusion criteria
- Diagnosis of major depressive disorder by a board-certified psychiatrist according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition
- Total score of the 17-item Hamilton Rating Scale for Depression (HAM-D) less than 7
- Aged between 18 to 35 years
- Right handedness
- Exclusion criteria
- A major depressive episode within the past three months
- Pacemaker or deep brain stimulation
- Metal implants in the head or neck area
- Other major mental disorders including autism spectrum disorders, mental retardation, psychotic disorders, bipolar disorders, obsessive-compulsive disorder, and neurocognitive disorders
- Alcohol or other illicit substance abuse
- Neurological diseases involving the central nervous system
- Major debilitating systemic diseases
- Pregnancy
- Breast feeding
- Cigarette smoker
- Color blindness
- Take part in another study within the last 4 weeks
Exclusion
Key Trial Info
Start Date :
May 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2023
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04708691
Start Date
May 1 2020
End Date
April 1 2023
Last Update
September 10 2021
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan, 100