Status:
UNKNOWN
Effects of COVID-19 on Endothelium in HIV-Positive Patients in Sub-Saharan Africa
Lead Sponsor:
Medical University of Graz
Collaborating Sponsors:
University of Olso
Kristiania University College
Conditions:
Covid19
Hiv
Eligibility:
All Genders
18+ years
Brief Summary
Background: Coronavirus disease 2019 (COVID-19) has affected almost every country in the world, especially in terms of health system capacity and economic burden. People from sub-Saharan Africa (SSA) ...
Detailed Description
Background: SARS-CoV-2 has affected almost every country worldwide with regard to health system capacities and economic burden, so far. The typical clinical presentations of COVID-19 are fever, sore ...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- PLHIV without antiretroviral therapy but with COVID-19 infection
- PLHIV with antiretroviral therapy and COVID-19 infection
- HIV-negative patients, sex- and age matched, infected with COVID-19;
- older than 18 years
- Exclusion criteria:
- Those with known co-infections such as hepatitis B and C
- with a viral load of HIV RNA \>1000 copies/ml under ART or with advanced symptoms of AIDS
- negative for SARS-CoV-2 RNA
Exclusion
Key Trial Info
Start Date :
February 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
342 Patients enrolled
Trial Details
Trial ID
NCT04709302
Start Date
February 1 2021
End Date
December 1 2025
Last Update
March 10 2023
Active Locations (3)
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1
University of Ilorin Teaching Hospital
Ilorin, Kwara State, Nigeria
2
Lagos Stae University Teaching Hospital Ikeja
Lagos, Nigeria
3
Walter Sisulu University
Mthatha, South Africa