Status:

ACTIVE_NOT_RECRUITING

Exploring the Utility of [18F]3F4AP for Demyelination Imaging in Controls, Neurodegeneration and Traumatic Brian Injury

Lead Sponsor:

Massachusetts General Hospital

Conditions:

Brain Injuries, Traumatic

Demyelinating Disorder

Eligibility:

All Genders

18-90 years

Phase:

PHASE1

Brief Summary

The overall objective is to obtain an initial assessment of the value of using \[18F\]3F4AP for imaging demyelinating diseases such as traumatic brain injury (TBI), neurodegenerative diseases such as ...

Eligibility Criteria

Inclusion

  • Subjects are 18 years of age and older, except AD subjects who are 60 to 90 years of age.

Exclusion

  • A subject will not be eligible for inclusion in this study if any of the exclusion criteria for PET/CT or MRI studies applies. A negative STAT quantitative serum hCG pregnancy test is required on the day of the PET/CT scan before female subjects of childbearing potential can participate. Any woman of childbearing potential, who is seeking to become pregnant, is breastfeeding, or who suspects she may be pregnant will not be enrolled in the study.

Key Trial Info

Start Date :

January 25 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2025

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT04710550

Start Date

January 25 2021

End Date

December 1 2025

Last Update

January 30 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114