Status:
UNKNOWN
Prophylactic Antibiotics in Prevention of Spontaneous Bacterial Peritonitis in Compensated Liver Cirrhosis
Lead Sponsor:
Assiut University
Conditions:
Liver Cirrhosis
Upper Gastrointestinal Bleeding
Eligibility:
All Genders
Brief Summary
timely short-term antibiotic prophylaxis is an essential step in the management of these patients . Prophylaxis must be instituted as early as variceal hemorrhage is suspected, and timely administrati...
Detailed Description
cute variceal bleeding is one of the major causes of death in cirrhotic patients . It is also the major cause of upper gastrointestinal (GI) bleeding in cirrhotic patients, accounting for 70% of cases...
Eligibility Criteria
Inclusion
- Child score "A" Cirrhotic patients
- Hematemesis and / or melena.
Exclusion
- Patient with unsuccessful endoscopic hemostasis
- Patients who already have signs of infections (elevation in the body temperature, elevation in white blood cells above 10,000 cell/mmᵌ);
- Patients with occult infection (defined as positive blood cultures obtained before antibiotic prophylaxis)
- Patients using antibiotics before endoscopy.
- Patients refuse to participate in the study.
Key Trial Info
Start Date :
December 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 30 2023
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04711122
Start Date
December 1 2022
End Date
April 30 2023
Last Update
October 28 2022
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