Status:

RECRUITING

Lasertherapy for Vulvodynia

Lead Sponsor:

Medical University of Graz

Conditions:

Vulvodynia

Eligibility:

FEMALE

18-80 years

Phase:

NA

Brief Summary

The study aims to assess the efficacy, acceptance and safety profile of vulvovaginal laser therapy in women with vulvodynia.

Detailed Description

Randomized double blinded sham-controlled clinical study Main hypothesis: Laser therapy will be more effective than sham laser therapy in vulvar pain reduction measured by Q-tip test and tampon test...

Eligibility Criteria

Inclusion

  • Women with vulvodynia (diagnosed according to the 2015 Consensus Terminology)
  • multidisciplinary treatment for at least 3 months
  • Informed consent

Exclusion

  • Current genital infection (i.e. candidiasis, herpes )
  • Inflammatory vulvar disease/ dermatosis (i.e. lichen sclerosus, lichen planus)
  • Neoplastic vulvar disease (e.g. HSIL Vulva, Paget disease)
  • Recent vulvar trauma (i.e. bleeding, erosion or ulceration)
  • Pudendal neuralgia
  • Pregnancy, delivery \<6 months
  • Epilepsy or major neurologic or psychiatric morbidity
  • Active systemic infection
  • Previous treatment with ionizing radiation in the area to be treated
  • History of wound healing disorders (i.e. hyperpigmentation, abnormal scarring)
  • Fever
  • Systemic or local autoimmune disorders
  • History of photosensitivity disorder

Key Trial Info

Start Date :

January 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 30 2026

Estimated Enrollment :

92 Patients enrolled

Trial Details

Trial ID

NCT04711369

Start Date

January 15 2021

End Date

July 30 2026

Last Update

March 4 2025

Active Locations (1)

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Department of Obstetrics and Gynecology/ Medical University of Graz

Graz, Austria, 8036