Status:
COMPLETED
Study of Perioperative Evolution of Right Heart Dysfunction and Preload Responsiveness in Open Heart Cardiac Surgery
Lead Sponsor:
Centre Hospitalier Universitaire de Saint Etienne
Conditions:
Cardiac Surgery
Eligibility:
All Genders
18+ years
Brief Summary
The aim of the study was to assess the ability a Lung Recruitment Maneuver (LRM) with a stepwise increase of PEEP to predict fluid responsiveness and right cardiac dysfunction in mechanically ventilat...
Eligibility Criteria
Inclusion
- Patients receiving an elective or urgent cardiac surgery with or without extracorporeal circulation under general anesthesia, under protective mechanical ventilation, monitored by invasive arterial blood pressure and pulse contour analysis (PICCO system) for cardiac output measurement and central venous pressure
Exclusion
- Left ventricular ejection fraction ≤ 30%
- heart arrhythmia, pulmonary hypertension (SPAP \> 35 mmHg)
- right heart failure (TAPSE \< 16 mm, S' at lateral tricuspid valve \< 10 cm/sec)
- lower limbs obstructive arteriopathy (stage IIb, III and IV)
- severe and very severe chronic obstructive pulmonary disease (COPD)
- pneumothorax and extreme weights (BMI \< 35 kg/m2).
Key Trial Info
Start Date :
February 3 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 29 2020
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04711798
Start Date
February 3 2020
End Date
May 29 2020
Last Update
February 4 2021
Active Locations (1)
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1
CHU de Saint-Etienne
Saint-Etienne, France