Status:

RECRUITING

Cerebral Blood Flow in Neonates During Major Cardiac Surgery.

Lead Sponsor:

UMC Utrecht

Conditions:

Hypoperfusion in Newborn With Congenital Heart Disease

Eligibility:

All Genders

Up to 6 years

Brief Summary

Rationale: During cardiac surgery, neonates are at high risk of cerebral damage: 36-78% will have new cerebral lesions after surgery. Adequate cerebral perfusion (CBF) is mandatory to prevent postoper...

Eligibility Criteria

Inclusion

  • Term infant aged \< 42 days / Preterm born \> 32 weeks and with a corrected age \< 42 days
  • (Semi-) elective cardiac of major non-cardiac surgery
  • Routine placement of an arterial cannula for invasive blood pressure monitoring.

Exclusion

  • Grade III-IV intracranial hemorrhage.
  • Emergency surgery or semi-elective surgery performed out of hours.
  • Informed consent from the parents is not obtained.

Key Trial Info

Start Date :

March 23 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2026

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04713605

Start Date

March 23 2022

End Date

January 1 2026

Last Update

March 27 2024

Active Locations (1)

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1

UMC Utrecht / Wilhelmina Children's Hospital

Utrecht, Netherlands, 3508GA