Status:
COMPLETED
Modulation of Memory Consolidation in Humans
Lead Sponsor:
University Medicine Greifswald
Collaborating Sponsors:
Technische Universität Berlin
Conditions:
Sleep
Eligibility:
All Genders
50-80 years
Phase:
NA
Brief Summary
The goal of the present study is to optimize effects of slow oscillatory transcranial direct current stimulation (so-tDCS) on sleep physiology and memory consolidation in humans by combining computati...
Detailed Description
Sleep plays an active role in long-term consolidation of memories. Specifically, slow oscillations (SO, large amplitude waves \<1 Hz) and sleep spindles (8-15 Hz), that can be measured by electroencep...
Eligibility Criteria
Inclusion
- Adults aged between 50-80 years
- screened as healthy in a structured telephone interview
Exclusion
- Mini Mental Status Examination scores below 24
- history of severe untreated medical, neurological, and psychiatric diseases
- sleep disorders
- alcohol or substance abuse
- brain pathologies identified on MRI scan
- intake of medication acting primarily on the central nervous system (e.g., antipsychotics, antidepressants, benzodiazepines, or any type of over-the-counter sleep-inducing drugs such as valerian),
- nonfluent German language abilities.
Key Trial Info
Start Date :
December 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2021
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT04714879
Start Date
December 1 2018
End Date
January 31 2021
Last Update
June 11 2024
Active Locations (1)
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1
University medicine Greifswald
Greifswald, Germany, 17475