Status:
RECRUITING
Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment
Lead Sponsor:
Vanderbilt University Medical Center
Conditions:
Parkinson Disease
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
The goal of this study is to learn more about the brain activity underlying Parkinson's disease cognitive impairment. The investigators will utilize neural recordings from corticostriatal structures p...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center
- Planned clinical electrode trajectory that contacts caudate
- Age greater than or equal to 40
- Diagnosis of Parkinson's disease
- Able to participate in intraoperative testing
- English speaking
- Exclusion criteria:
- Age less than 40
- Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)
- Movement disorder other than Parkinson's disease
Exclusion
Key Trial Info
Start Date :
June 2 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2026
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT04715984
Start Date
June 2 2021
End Date
February 1 2026
Last Update
October 21 2025
Active Locations (1)
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1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232