Status:

COMPLETED

Effects of Insomnia Treatment on Metabolism in Patients With Depression

Lead Sponsor:

University of Pennsylvania

Collaborating Sponsors:

Doris Duke Charitable Foundation

Conditions:

Insomnia Chronic

Insomnia

Eligibility:

All Genders

21-60 years

Phase:

NA

Brief Summary

This project will examine changes in metabolism and depressive symptoms after receiving CBT-I in 30 subjects with insomnia disorder and MDD.

Eligibility Criteria

Inclusion

  • Insomnia Severity Index \> 14
  • Meet diagnostic criteria for Insomnia
  • Meet diagnostic criteria for Major Depressive Disorder
  • Either currently taking an SSRI/SNRI or no antidepressant

Exclusion

  • BMI \> 30
  • Those with unstable medical conditions defined by change in diagnosis or medication in past 2 months
  • Those with clinically significant comorbid psychiatric conditions (e.g., Bipolar disorder)
  • Those with known untreated sleep apnea or other clinically significant sleep disorder other than insomnia
  • Those currently taking medications that affect sleep or metabolism (e.g., stimulants, thyroid meds)

Key Trial Info

Start Date :

December 20 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 20 2022

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT04719143

Start Date

December 20 2018

End Date

December 20 2022

Last Update

January 17 2023

Active Locations (1)

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1

The University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104