Status:
UNKNOWN
Drug and Dose Adjustment in Preventing Postoperative Nausea and Vomiting
Lead Sponsor:
Jordan Hospital
Conditions:
Postoperative Nausea and Vomiting
Eligibility:
All Genders
18-70 years
Brief Summary
The aim is to evaluate the effectiveness of different regimens of prophylactic Ondansetron, Dexamethasone, or both, on the incidence and severity of post-operative nausea and vomiting.
Detailed Description
Patients will be randomized to one of four arms: Ondansetron (4O-PE: 4 mg Ondansetron pre-emergence, 8O-PE: 8 mg Ondansetron pre-emergence, 4O-PI: 4 mg Ondansetron pre-incision, 8O-PI: 8 mg Ondansetro...
Eligibility Criteria
Inclusion
- ASA grade I and II
- Aged 18-70 years
- Patients scheduled for elective surgery under general anesthesia
Exclusion
- All patients who received antiemetics or cortisone within 48 hr before surgery
- Pregnant, breast feeding ladies
- Any patient with BMI (Body Mass Index) \> 34 kg/m²
- Patient with gastrointestinal, hepatic, renal, mental or psychiatric illnesses were also excluded from the study protocol.
Key Trial Info
Start Date :
May 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 20 2024
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT04719741
Start Date
May 1 2023
End Date
August 20 2024
Last Update
March 29 2022
Active Locations (1)
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1
Jordan Hospital
Amman, Jordan, 11152