Status:
COMPLETED
Circadian Melatonin Rhythms in Critically Ill Patients With Delirium
Lead Sponsor:
University Hospital, Basel, Switzerland
Collaborating Sponsors:
Centre for Chronobiology, Transfaculty Research Platform Molecular and Cognitive Neurosciences (MCN), Psychiatric Hospital of the University of Basel (UPK)
Conditions:
ICU Delirium
Eligibility:
All Genders
55+ years
Brief Summary
Delirious patients often suffer from sleep disturbances such as insomnia, sleep fragmentation, daytime somnolence, and reversal of sleep-wake rhythms. There is evidence, that patients suffering from h...
Detailed Description
Delirium is a highly prevalent neuropsychological condition in patients admitted to the ICU. Occurrence of a delirium in critically ill patients is associated with prolonged ICU stay and longer hospit...
Eligibility Criteria
Inclusion
- Adult patients (aged 55 years or older)
- Admission to the ICU
- Current delirium (ICDSC ≥4)
- Functioning venous or arterial line for blood sample collection
Exclusion
- Delirium prior to ICU admission
- Intake of beta blockers within 48 hours before study inclusion and during study period
- Premenopausal women
- Terminal state
- Dementia
- Substance abuse including alcohol in current medical history
Key Trial Info
Start Date :
March 31 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 25 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04721613
Start Date
March 31 2021
End Date
May 25 2023
Last Update
December 7 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital Basel
Basel, Switzerland, 4031