Status:
ACTIVE_NOT_RECRUITING
Optimal Nutrition for Prevention of Hypertension in Pregnancy
Lead Sponsor:
University of Ulster
Collaborating Sponsors:
DSM Ltd
Public Health Agency (Northern Ireland)
Conditions:
Blood Pressure
Pregnancy
Eligibility:
FEMALE
18+ years
Phase:
NA
Brief Summary
The aim of this study is to investigate the role of the 677C→T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene on blood pressure (BP) during pregnancy, and to examine the effect o...
Detailed Description
The overall aim of this study is to investigate the role of a common genetic polymorphism in folate metabolism, MTHFR 677C→T, on blood pressure (BP) during pregnancy and the impact of B-vitamin supple...
Eligibility Criteria
Inclusion
- • Women with a singleton pregnancy who are in their first trimester of pregnancy
Exclusion
- Patients who have a high risk pregnancy, a previous pregnancy with a neural tube defect (NTD) or are the first degree relative of a woman who had a pregnancy affected by NTD or are themselves a sufferer of an NTD
- Women who are taking medication known to interfere with B-vitamin metabolism
Key Trial Info
Start Date :
March 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
2250 Patients enrolled
Trial Details
Trial ID
NCT04723836
Start Date
March 1 2017
End Date
December 31 2025
Last Update
October 7 2025
Active Locations (3)
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1
Letterkenny University Hospital
Letterkenny, Ireland
2
Northern Health and Social Care Trust
Coleraine, N.Ireland, United Kingdom, BT52 1HS
3
Western Health and Social Care Trust
Londonderry, N.Ireland, United Kingdom, BT47 6SB