Status:
COMPLETED
Effect of GnRH Agonist vs GnRH Antagonist on IVF/ICSI Outcomes.
Lead Sponsor:
Damascus University
Conditions:
In Vitro Fertilization
Intracytoplasmic Sperm Injection
Eligibility:
FEMALE
18-39 years
Phase:
PHASE4
Brief Summary
The aim of this prospective, non-randomised, open-label, clinical trial is to compare the effects of two pituitary suppression regimens; GnRH Agonist-Long Protocol and GnRH Antagonist-Flexible Protoco...
Eligibility Criteria
Inclusion
- Women undergoing IVF/ICSI.
- Age: 18-39 years.
- Both ovaries present.
Exclusion
- Age ≥ 40 years.
- History of three or more previous IVF failures.
- Patients with hormonal disorders like hyperprolactinemia, thyroid disorders.
- Patients with Polycystic ovary syndrome.
- Patients who previously undergo Unilateral Oophorectomy.
- Patients with chronic diseases: diabetes mellitus, cardiovascular diseases, liver diseases, kidney diseases.
- Patients with diseases may affect IVF outcomes: Endometriosis, uterine fibroids, Hydrosalpinx, Adenomyosis, autoimmune diseases,
- Cancer.
Key Trial Info
Start Date :
December 22 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 5 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04724343
Start Date
December 22 2019
End Date
July 5 2022
Last Update
October 24 2023
Active Locations (1)
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1
Orient Hospital
Damascus, Syria