Status:
RECRUITING
Progesterone as Luteal Support in Frozen IVF Natural Cycles
Lead Sponsor:
Vastra Gotaland Region
Collaborating Sponsors:
Göteborg University
Conditions:
Infertility
Embryo Transfer
Eligibility:
FEMALE
18-43 years
Phase:
PHASE4
Brief Summary
The ProFET study aims to investigate if luteal phase support by vaginal progesterone, is superior to no luteal phase support, in terms of live birth rate per woman after a frozen embryo transfer (FET)...
Detailed Description
Vaginal progesterone supplementation is routine treatment after IVF with fresh embryo transfer, but it is uncertain whether vaginal progesterone after frozen embryo transfer in natural cycles is effic...
Eligibility Criteria
Inclusion
- Planned for a FET-NC with a blastocyst
- BMI \>18.5 \<35
- Regular menstrual cycles 24-35 days
- Given informed consent
- Understand written and spoken Swedish, English or Arabic
Exclusion
- Oocyte donor cycles, preimplantation genetic testing (PGT) cycles. Uterine malformation, submucous myoma and endometrial polyps.
- Hypersensitivity against study medication. Other contraindications according to www.fass.se
- Development of serious disease contraindicating ART or pregnancy.
- Participation or recent participation in a clinical study with an investigational product (past 30 days). Previous participation in this study.
Key Trial Info
Start Date :
May 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
1800 Patients enrolled
Trial Details
Trial ID
NCT04725864
Start Date
May 1 2021
End Date
December 31 2025
Last Update
April 24 2024
Active Locations (1)
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1
Department of Reproductive Medicine
Gothenburg, Sweden, S-41345