Status:

TERMINATED

Open Label Study to Collect Clinical Data to Document Clinical Performance and Safety in Total Knee Arthroplasty

Lead Sponsor:

Corin

Conditions:

Total Knee Arthroplasty

Knee Disease

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to evaluate clinical performance and safety in total knee arthroplasty using HLS implants.

Detailed Description

It is planned to collect prospective and retrospective data from a continuous and exhaustive series of patients in a French center where Total Knee Arthroplasty with HLS prosthesis is performed routin...

Eligibility Criteria

Inclusion

  • For the HLS-1, HLS-2, HLS Evolution and HLS Noetos retrospective group:
  • Adult patients older than 18 years old.
  • Patients who have undergone routine preoperative clinical evaluations prior to their Total Knee Replacement surgery and implanted with one of the following prostheses from the HLS range: HLS-1, HLS-2, HLS Evolution and HLS Noetos between their first date of use in 1987 and their last date of use as normal practice at the participating site in accordance to indications and intended use as described in the Instruction for Use (IFU) of the study devices.
  • Patients who have been informed about their participation into an observational study.
  • For the HLS KneeTec prospective group (with retrospective surgeries):
  • Adult patients older than 18 years old.
  • Patients who have undergone routine preoperative clinical evaluations and received a TKR or are suitable candidates for a TKR with a fixed or mobile postero-stabilized HLS KneeTec prosthesis (cementless, cemented or hybrid combination) for the treatment of a primary or secondary knee osteoarthritis and inflammatory disease such as rheumatoid arthritis in accordance to indications and intended use as described in the Instruction for Use (IFU) of the study devices.
  • Patients who are willing and able to complete the scheduled FU visits.
  • Patients who have been informed about their participation into an observational registry study

Exclusion

  • Patients mentally incompetent or unable to understand what participation in the study entails.
  • Patients who present signs and symptoms of any of the known contraindications described in the Instruction for Use (IFU) of the study devices.
  • Patients who deny their participation into the study.

Key Trial Info

Start Date :

December 15 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 1 2023

Estimated Enrollment :

2146 Patients enrolled

Trial Details

Trial ID

NCT04727060

Start Date

December 15 2011

End Date

November 1 2023

Last Update

July 16 2024

Active Locations (1)

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1

Hopital de la Croix-Rousse, Hospices Civils de Lyon

Lyon, France, 69000