Status:
UNKNOWN
Effect of Targeted Temperature Management on Cerebral Autoregulation in Patients With Neurocritical Diseases
Lead Sponsor:
Xiangya Hospital of Central South University
Conditions:
Ischemic Stroke
Subarachnoid Hemorrhage, Aneurysmal
Eligibility:
All Genders
18+ years
Brief Summary
Change and effect of cerebral autoregulation during targeted temperature management in neurocritical patients
Detailed Description
Cerebral autoregulation (CA) is the ability of cerebral vascular system to contract or diastole with the change of perfusion pressure, and to maintain the stability of cerebral blood flow. It has been...
Eligibility Criteria
Inclusion
- \- Aneurysmal subarachnoid hemorrhage (aSAH), Traumatic brain injury (TBI), Acute ischemic stroke (AIS), Intracerebral hemorrhage (ICH), Ischemic hypoxic encephalopathy (HIE), sepsis-associated encephalopathy (SAE) who need to reduce the core temperature to normal.
Exclusion
- Age \< 18 years old;
- Pregnancy;
- The temporal window was limited and the image could not be obtained;
- Patients with bradycardia induced by common carotid artery compression and intolerant of THRT
- Patients with severe carotid artery disease;
- Uncorrected severe coagulation disorders and active bleeding;
- Patients without informed consent;
- Patients who had been treated with hypothermia before inclusion
Key Trial Info
Start Date :
January 22 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2021
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04728438
Start Date
January 22 2021
End Date
July 1 2021
Last Update
January 28 2021
Active Locations (1)
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1
Xiangya Hospital Central South University
Changsha, Hunan, China, 410008