Status:

COMPLETED

Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population

Lead Sponsor:

Esraa Hassan,MD

Collaborating Sponsors:

South Egypt Cancer Institute

Conditions:

Colo-rectal Cancer

Eligibility:

All Genders

25-65 years

Brief Summary

1. Determination of expression level of HOTTIP and EIF4EBP1(Eukaryotic translation initiation factor 4E-binding protein 1) . 2. Investigation of the SNP HOTTIP rs1859168 and it's association with CRC ...

Detailed Description

Colorectal cancer (CRC) is a common digestive tract tumor 1.It is the third leading cause of death in the world. Overall 5-year survival rate is less than 40%, and the occurrence is rising 2. However,...

Eligibility Criteria

Inclusion

  • No sex predilection.
  • Age (25-65 yr).
  • Colorectal carcinoma confirmed by histopathological examination

Exclusion

  • -patients who received any treatment.
  • Cases with other organ cancers.
  • History of chemotherapy and radiotherapy.
  • Systemic diseases such as renal failure, diabetes mellitus, and hypertension.

Key Trial Info

Start Date :

April 15 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 20 2024

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04729855

Start Date

April 15 2022

End Date

September 20 2024

Last Update

April 30 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Assiut University

Asyut, Egypt