Status:
UNKNOWN
Dentifrice With Innovative Remineralizing Technology
Lead Sponsor:
Federal University of Paraíba
Conditions:
Initial Dental Caries
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Objective: The aim of this study is to evaluate in vivo dentifrices containing different active ingredients in fluoride (F) retention in saliva and dental biofilm. Material and methods: The dentifrice...
Detailed Description
A randomized, duple-blind crossover clinical trial study was performed to evaluate the bioavailability of intraoral fluoride in biomarkers of exposure (biofilm and saliva) after the use of dentifrice ...
Eligibility Criteria
Inclusion
- The eligibility criteria were people over 18 years old, without systemic commitment and living in the city of João Pessoa-Paraíba, without water fluoridation (\< 0.1 μg/mL F).
Exclusion
- Individuals were excluded if they used drugs that interfere with biofilm formation and salivary flow or fluoride products (\> 5000 ppm) in the last 4 weeks, used orthodontic appliances, or had cavity lesions, periodontal disease, and/or tooth sensitivity.
Key Trial Info
Start Date :
February 3 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 12 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04730908
Start Date
February 3 2020
End Date
April 12 2023
Last Update
February 8 2023
Active Locations (1)
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1
Federal University of Paraíba
João Pessoa, Paraíba, Brazil