Status:
UNKNOWN
Physiologic Changes of Posterior Ocular Segment During the Menstrual Cycle
Lead Sponsor:
Khon Kaen University
Conditions:
Retinal Vascular
Eligibility:
FEMALE
25-40 years
Phase:
NA
Brief Summary
Changes of luteinizing hormone (LH), estrogen and progesterone during the menstrual cycle influence the ocular physiology in both anterior and posterior segments. From the literature review, there wer...
Detailed Description
There were 2 studies of posterior segment changes during the menstrual cycle. Akar et al showed significant decrease of neuroretinal rim area and increase of cupt area in late luteal phase. Ulas et al...
Eligibility Criteria
Inclusion
- Female with age 25-40 yr
- Normal body mass index (18.5-24.9)
- Regular menstrual cycle (28-32 days)
- Written informed consent
Exclusion
- Pregnant women
- Lactating women
- Having childbirth or miscarriage within 6 months
- Systemic diseases which need taking the regular medication
- History of ocular disease such as glaucoma, retinal vascular diseases and macular disease
- History of hormonal taking such as oral contraceptive pills within 6 months
- History of intraocular laser and intraocular surgery
- Refractive error; spherical equivalent \>4 diopters
- Can not taking the images by Optovue® such as spine diseases
- Withdrawal criteria
- Pregnancy detection during the study period
- Receiving sex hormone during the study period such as emergency contraceptive pills
Key Trial Info
Start Date :
September 3 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2023
Estimated Enrollment :
39 Patients enrolled
Trial Details
Trial ID
NCT04731207
Start Date
September 3 2021
End Date
December 30 2023
Last Update
October 10 2023
Active Locations (1)
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1
Khon Kaen University
Khon Kaen, Thailand, 40000