Status:
COMPLETED
Systemic Inflammation During Recanalization of Cerebral Arterial Occlusion
Lead Sponsor:
Hospices Civils de Lyon
Conditions:
Stroke
Systemic Infection
Eligibility:
All Genders
18+ years
Brief Summary
Strokes management, secondary to proximal arterial occlusion, by endovascular thrombectomy (TM) is now well established. The immuno-inflammatory events of reperfusion after TM are discussed. Systemic ...
Eligibility Criteria
Inclusion
- GROUP "AVC" :
- Adults patient (s)
- Ischemic stroke by occlusion of a middle cerebral artery (proximal portion M1)
- Initial diagnostic MRI infusion
- TM with complete reperfusion (TICI 2b, 2c or 3)
- TM performed under local anesthesia +/- anxiolysis, or sedation including propofol
- mRS prior to stroke \<2
- Barthel index \<90
- Included in the HIBISCUS cohort
- Patient who was informed and did not object to participating in the study OR included through the emergency procedure then collection of his non-objection or that of his trusted person as soon as possible
Exclusion
- NIHSS awareness score\> or = 2
- Haemorrhagic complication before thrombectomy
- Pregnant woman
- Multiple vascular occlusions
- Occlusions of posterior or anterior cerebral territories other than M1
- Protected major
- TM performed under general anesthesia
- Other vital failure than neurological failure
- GROUP "CONTROL" :
- Inclusion Criteria:
- Adults patient (s)
- mRS \<2
- Barthel index \<90
- Requiring diagnostic arteriography for routine check-up of a cerebrovascular malformation
- Patient who was informed and did not object to participating in the study
Key Trial Info
Start Date :
April 7 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 12 2021
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT04731584
Start Date
April 7 2021
End Date
June 12 2021
Last Update
February 13 2023
Active Locations (4)
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1
Service d'Anesthésie Réanimation Hôpital - Neurologique/Groupement Est
Bron, France, 69500
2
Service de Neurologie vasculaire - Hôpital Neurologique/Groupement Est
Bron, France, 69500
3
Service de Neuroradiologie interventionnelle - Hôpital Neurologique/Groupement Est
Bron, France, 69500
4
Service d'Anesthésie Réanimation - Hôpital Edouard Herriot/Groupement Centre
Lyon, France, 69437