Status:
COMPLETED
Using Omics Technology to Explore the Mechanism of Acupuncture Treatment of Different Acupoints of Knee Osteoarthritis
Lead Sponsor:
China Medical University Hospital
Collaborating Sponsors:
National Health Research Institutes, Taiwan
Conditions:
Acupuncture Therapy
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
In recent years, commonly used Omics techniques, including genomics, proteomics, metabolomics, have been applied in the studies on the mechanism of acupuncture effect. In the previous study, "Immediat...
Detailed Description
Introduction: In recent years, commonly used Omics techniques, including genomics, proteomics, metabolomics, have been applied in the studies on the mechanism of acupuncture effect. In the previous s...
Eligibility Criteria
Inclusion
- Subjects will be recruited when they meet the Clinical Classification Criteria for KOA, that is knee pain and three out of six symptoms can be found in clinical practices, as recommended by the American College of Rheumatology:
- any gender aged 50 years or above;
- have less than 30 minutes of morning stiffness;
- crepitus on active motion;
- bony tenderness;
- bony enlargement;
- no palpable warmth.
Exclusion
- Subjects with malignancy, any acute medical condition, poorly controlled diabetes or hypertension, a motor or sensory nerve defect, blood clotting disease, mental illness, dementia, mental retardation or other abnormal person on the organic mind.
- Subjects with intra-articular solid or hyaluronic acid injection in the past 3 months.
- Subjects have undergone knee surgery, knee trauma, congenital knee deformation, severe knee varus or valgus deformation, or endocrine, metabolic, infectious, inflammatory, secondary degenerative knee arthritis caused by problems with rheumatic immune diseases.
- unable to walk.
- Subjects who are hypersensitive to needles.
- Those who are unwilling to cooperate and sign the subject's consent form after explaining and explaining the clinical trial process and purpose.
Key Trial Info
Start Date :
October 12 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 12 2021
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04733352
Start Date
October 12 2020
End Date
September 12 2021
Last Update
January 23 2024
Active Locations (2)
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1
Yiyuantang Chinese Medicine Clinic
Hsinchu, Taiwan
2
China Medical University Hospital
Taichung, Taiwan, 404