Status:
COMPLETED
Interest of Eosinopenia to Predict In-hospital Mortality Among Elderly Patients
Lead Sponsor:
Centre d'Investigation Clinique et Technologique 805
Conditions:
Death
Bacterial Infections
Eligibility:
All Genders
Brief Summary
No biological marker is highly specific of infection and currently available, especially for bacterial infection. The ideal marker would be easy to perform, rapidly, inexpensive, and correlated with t...
Detailed Description
We performed an observational, retrospective single-center study in a teaching hospital of Paris area (Ambroise Paré Hospital in Boulogne-Billancourt). The hospital information system that is routinel...
Eligibility Criteria
Inclusion
- Eligible patients were hospitalized in acute geriatrics ward between January 1 and December 31, 2018 with a diagnosis of bacterial infection coded in the medical chart and completed by healthcare staff for the financing of hospital activity.
- Infections of interest were pulmonary, urinary, digestive, biliary, cutaneous, cardiac, and central nervous system infections, as well as bacteremia.
- A White blood count cell with eosinophil count available at day 0 from admission, day 3 +/-1 day
Exclusion
- bone and joint infections because of specificities in the management of these infections (e.g. surgical procedures)
- Disease that could influence the eosinophil count or that could be the cause of diagnostic errors:
- Acquired immunosuppression: HIV associated with a CD4 count of less than 200/mm\^3, immunosuppressive treatments (corticosteroid therapy at a dose ≥10 mg/d prednisone equivalent, anti-cancer chemotherapy, methotrexate etc.)
- Previous known haematological disorders
- Discrepancies between the hospital coding of International Classification of Diseases (ICD-10) and the diagnosis of bacterial infection into the medical chart • Patients already on antibiotic therapy for more than 48 hours before the inclusion
Key Trial Info
Start Date :
January 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2020
Estimated Enrollment :
224 Patients enrolled
Trial Details
Trial ID
NCT04734431
Start Date
January 1 2018
End Date
January 1 2020
Last Update
February 2 2021
Active Locations (1)
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1
Benjamin Davido
Garches, France, 92380