Status:
UNKNOWN
Muscle Quality Index Improvement by Exercise and HMB Oral Supplementation in Older Adults
Lead Sponsor:
Instituto Nacional de Rehabilitacion
Conditions:
Aging Well
Eligibility:
All Genders
65-75 years
Phase:
NA
Brief Summary
The aging process is accompanied by a decrease in several biological and physical functions, which have an impact on the perception of well-being and quality of life. Among these, the decrease in musc...
Detailed Description
Study design: this is a 14-week, randomized controlled trial. 76 participants will be recruited from the medical services of the National Institute of Rehabilitation (NIR). Participants: Adults betwe...
Eligibility Criteria
Inclusion
- Body mass index 25-30 km/m\^2
- Appendicular skeletal muscle mass index in women ≥ 5.0 kg/m\^2 and men ≥ 6.0 kg/m\^2
- No regular exercise
- Non-smokers
- Compensated comorbidities
- Without consumption of nutritional supplements
Exclusion
- Osteoporosis
- Cardiovascular diseases (recent heart attack, unstable angina, heart failure, complete atrioventricular block)
- Musculoskeletal injuries
- Severe cognitive impairment
- Major depressive disorder
- Thyroid diseases
- Anemia with no response to previous treatment in the last 3 months
- b2-adrenergic agonists, glucocorticoids, diuretics or peripheral vasodilators users
- With amino acid and vitamin D supplementation or suspended with less than 3 months
- Data of renal insufficiency
- Chronic obstructive pulmonary disease
- Malabsorption syndrome associated with malnutrition
- High risk of falls evaluated with the Tinetti scale (score ≤19)
- Frailty syndrome
Key Trial Info
Start Date :
June 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2024
Estimated Enrollment :
76 Patients enrolled
Trial Details
Trial ID
NCT04734951
Start Date
June 1 2023
End Date
August 1 2024
Last Update
March 20 2023
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