Status:

RECRUITING

Investigating Inhibitory Control Networks in Parkinson's Disease

Lead Sponsor:

University of Alabama at Birmingham

Collaborating Sponsors:

National Institute of Neurological Disorders and Stroke (NINDS)

Conditions:

Parkinson Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to investigate the brain activity associated with non-motor symptoms of movement disorders, including Parkinson's disease and essential tremor. These movement disorders co...

Detailed Description

Movement disorders are a prominent cause of disability worldwide. In the United States, it is estimated that more than 4 million people suffer from Parkinson's disease (PD), essential tremor (ET), and...

Eligibility Criteria

Inclusion

  • Eligible for surgery based on multi-disciplinary consensus review
  • Have a diagnosis of Parkinson's disease or Essential Tremor
  • Have a diagnosis of medically-refractory movement disorder (Parkinson's disease, Essential Tremor, or dystonia)
  • Willingness to participate in the paradigms described in the protocol

Exclusion

  • Inability to provide full and informed consent
  • Age younger than 18
  • Are not able to participate in study-related activities
  • History of prior ischemic/hemorrhagic stroke, subdural hemorrhage, or seizure

Key Trial Info

Start Date :

April 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 31 2028

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT04735458

Start Date

April 1 2021

End Date

March 31 2028

Last Update

December 2 2025

Active Locations (1)

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University of Alabama at Birmingham

Birmingham, Alabama, United States, 35233