Status:

UNKNOWN

Chronotherapy for Radiotherapy of Glioma

Lead Sponsor:

General Hospital of Ningxia Medical University

Conditions:

To Determine Whether the Timing of Radiotherapy Has an Effect on Patient Outcomes

Eligibility:

All Genders

18-80 years

Brief Summary

This study aims to determine if there is any difference in the efficacy of radiotherapy for glioma outcomes in the morning or in the evening. The study team believes that there may be a benefit to tak...

Detailed Description

The objective of this study is to determine whether the timing of radiotherapy to treat glioma has an effect on patient outcomes. Primary objective: Determine whether there is a difference in outcome...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years;
  • Pathological or cytological diagnosis of glioma;
  • Normal liver and kidney function.

Exclusion

  • Pregnant or lactating women;
  • Second primary malignancy;
  • Severe lung infection;
  • with high blood pressure although treated with medication;
  • Patients with myocardial ischemia or myocardial infarction, arrhythmia (including QT interval \> 440 ms) or grade II cardiac insufficiency;
  • Arteriovenous thrombosis in 6 months prior to first administration, Such as cerebrovascular accident (including temporary ischemic attack), deep vein thrombosis and pulmonary embolism;
  • Serious heart, lung and bone marrow impairment;
  • History of severe hypertension or cerebral hemorrhage

Key Trial Info

Start Date :

February 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2021

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04735939

Start Date

February 1 2021

End Date

December 31 2021

Last Update

February 3 2021

Active Locations (1)

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General Hospital of Ningxia Medical University

Yinchuan, Ningxia, China, 750004