Status:
UNKNOWN
Ketone Supplements and Substrate Oxidation and Physical Performance
Lead Sponsor:
United States Army Research Institute of Environmental Medicine
Conditions:
Ketosis
Glucose Metabolism
Eligibility:
All Genders
18-39 years
Phase:
NA
Brief Summary
The objective of this randomized crossover study is to examine the influence of consuming a ketone ester plus carbohydrate (KE+CHO) supplement on substrate oxidation and physical performance in 15 hea...
Detailed Description
Following an overnight (10 hour) fast, two catheters will be placed into the lower arm (one in each arm). One arm will be used for infusion of 6,6-\[2H2\] glucose tracer and the other will be used for...
Eligibility Criteria
Inclusion
- Men and women aged 18 - 39 years
- Body mass index (BMI) \< 30 kg/m2
- Routinely participate in aerobic and/or resistance exercise at least 2 days per week
- Refrain from the use of caffeine, alcohol, dietary supplements, and nicotine while consuming study diets
- Supervisor approval to participate for active duty military and federal civilian employees working within the US Army Natick Soldier Systems Center
Exclusion
- Metabolic or cardiovascular abnormalities, gastrointestinal disorders (i.e., kidney disease, diabetes, cardiovascular disease, etc.)
- Disease or medication (i.e., diabetes medications, statins, corticosteroids, etc) that affects macronutrient utilization and/or the ability to participate in strenuous exercise
- Allergies or intolerance to foods (including but not limited to lactose intolerance/milk allergy) to be utilized in the study or vegetarian practices
- Present condition of alcoholism, anabolic steroids, or other substance abuse issues
- Musculoskeletal injuries that compromise the ability to exercise
- Not willing to avoid non-study exercise and foods during each of the 3 day testing periods
- Blood donation within 8 weeks of beginning the study
- Pregnant or breast feeding
Key Trial Info
Start Date :
November 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2022
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT04737694
Start Date
November 1 2020
End Date
September 1 2022
Last Update
October 14 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
USARIEM
Natick, Massachusetts, United States, 01760