Status:
COMPLETED
Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke
Lead Sponsor:
Mazandaran University of Medical Sciences
Conditions:
Ischemic Stroke
Transient Ischemic Attack
Eligibility:
All Genders
40+ years
Phase:
PHASE3
Brief Summary
This is a randomized, controlled, active comparator arm, outcome assessor blind, parallel group design on 90 patient with diagnosis of ischemic stroke admitted in Bou-Ali Sina Hospital, Sari,Iran.The ...
Detailed Description
This is a randomized, controlled, parallel, active comparator arm, outcome assessor blind, feasibility study. The aim of study is assess the efficacy of ticagrelor plus aspirin in reduce of minor non-...
Eligibility Criteria
Inclusion
- signing inform consent,
- recent ischemic stroke within 24 h,
- diagnosed by brain CT or MRI mild stroke with NIHSS =\<8 and no evidence of large infarct in brain imaging
- high risk TIA with ABCD \>4,
- no cardioembolic source such as low E/F, MS, AF ,...
- no specific etiology such as dissection, vasculitis, ...
- no carotid stenosis \> 50 % in side of involvement
Exclusion
- history of hypersensitivity to consumptive drug
- any indication for anticoagulant therapy
- acute phase treatment with intravenous thrombolysis or thrombectomy
- any contraindication for consumptive drug
- history of intracranial hemorrhage
- history of GI bleeding during past 6 m
- candidate for endarterectomy
- history of coagulopathy
- active hemorrhagic diathesis during randomization
Key Trial Info
Start Date :
August 8 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 15 2023
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT04738097
Start Date
August 8 2021
End Date
October 15 2023
Last Update
October 19 2023
Active Locations (2)
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1
Athena Sharifi Razavi
Sari, Mazandaran, Iran, 4818777111
2
Bou-Ali Sina hospital , Mazandarn University of Medical Science
Sari, Iran