Status:
COMPLETED
Effect of Low-level Laser Therapy on Salivary Flow, pH and Quality of Life in Irradiated Oropharyngeal Cancer Patients
Lead Sponsor:
Ziauddin University
Conditions:
Xerostomia
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
There are multiple treatment modalities for head and neck cancer. They include radiation therapy, chemotherapy and surgery. Radiation therapy aims to control the tumor with minimum damage to adjacent ...
Detailed Description
There are multiple treatment modalities the cancers of the head and neck. The main three major treatment options are surgery, radiation therapy and chemotherapy. Radiation therapy (RT) is used to cont...
Eligibility Criteria
Inclusion
- Patients with radiation induced persistent xerostomia which will be confirmed clinically and by taking salivary flow rate. Patients which will have salivary flow rate less than 0.1-0.2 ml/min shall be included.
- Patients treated with therapeutic RT for oropharyngeal cancers 3 to 36 months ago
- Patients whose age was equal to or more than 18 years irrespective of gender.
Exclusion
- Patients with other determined causes of xerostomia which have been confirmed. Systemic conditions (specially checking and excluding patients having dehydration,patients with known diseases of salivary glands, salivary glands removal surgery, smoking, diabetes, and autoimmune disorders among such as Sjögren's syndrome and drugs that cause xerostomia.
Key Trial Info
Start Date :
November 6 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 3 2021
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT04738227
Start Date
November 6 2020
End Date
February 3 2021
Last Update
July 30 2021
Active Locations (1)
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1
Ziauddin University
Karachi, Sindh, Pakistan, 75500