Status:
COMPLETED
Autologous Bone Marrow Concentrate in Knee Osteochondral Allograft Transplantation
Lead Sponsor:
Rush University Medical Center
Collaborating Sponsors:
Joint Restoration Foundation
Conditions:
Cartilage Injury
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
The goal of this study is to establish if mesenchymal stem cell augmentation improves graft incorporation and to analyze the cytokine environment of the joint after osteochondral allograft transplanta...
Detailed Description
Articular cartilage injuries in the knee continue to grow in number as detection and treatment options have advanced. Treatment options, including microfracture, autologous chondrocyte (cells that mak...
Eligibility Criteria
Inclusion
- • Patients aged 18-50 with a cartilage defect indicated for treatment with osteochondral allograft
Exclusion
- Patients with known rheumatoid arthritis, any other inflammatory arthropathy or synovial tissue disorder.
- Patients with known bipolar osteoarthritis of the knee as determined by the treating physician, greater than Kellegren-Lawrence Grade 3 on x-ray imaging
- Patient with a known infection or history of infection in the affected knee
Key Trial Info
Start Date :
March 2 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 12 2023
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT04739930
Start Date
March 2 2018
End Date
January 12 2023
Last Update
January 13 2023
Active Locations (1)
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1
Rush University Medical Center
Chicago, Illinois, United States, 60612