Status:
COMPLETED
Non-interventional, Prospective Study to Determine Prevalence of EGFR Mutations in Non-small Cell Lung Cancer
Lead Sponsor:
AstraZeneca
Conditions:
Non-small Cell Lung Cancer
Eligibility:
All Genders
18+ years
Brief Summary
This prospective, multicountry, multicentre, non-interventional study plans to include patients who have undergone surgery for early-stage (IA to IIIB on the basis of pathologic criteria) non-squamous...
Detailed Description
This prospective, multicountry, multicentre, non-interventional study plans to include patients who have undergone surgery for early-stage (IA to IIIB on the basis of pathologic criteria) non-squamous...
Eligibility Criteria
Inclusion
- Adult male or female patients ≥18 years old or 'adults' according to age of majority as defined by the local regulations
- Patient or next of kin/legal representative is willing and able to provide informed consent according to the local regulations, where applicable
- Patients with stage IA to IIIB (on the basis of pathologic criteria) NSCLC with adenocarcinoma, or mixed histology with an adenocarcinoma component who have undergone surgical resection of the tumour during the preceding 6 weeks
- Availability of FFPE tissue specimen suitable for EGFRm testing (either the primary diagnostic sample or the surgically resected tumour specimen)
- Availability of medical records at the participating site detailing the initial diagnosis, staging, and surgical management of NSCLC
Exclusion
- Patients who fulfil any of the following exclusion criteria will not be eligible for the study:
- Histology of the tumour is considered not to be of primary lung in origin
- Histology is pure squamous cell carcinoma, pure small cell carcinoma, or large cell carcinoma origin lacking any immunohistochemistry evidence of adenocarcinoma differentiation -
Key Trial Info
Start Date :
March 4 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 30 2022
Estimated Enrollment :
601 Patients enrolled
Trial Details
Trial ID
NCT04742192
Start Date
March 4 2021
End Date
November 30 2022
Last Update
August 14 2023
Active Locations (33)
Enter a location and click search to find clinical trials sorted by distance.
1
Research Site
Rosario - Santa Fe, Argentina, Argentina, S2002RE
2
Research Site
Buenos Aires, Argentina, 1415
3
Research Site
Santiago, Chile, 13123
4
Research Site
Santiago, Chile, 7500713