Status:

COMPLETED

In-hospital Versus After-discharge Complete Revascularization

Lead Sponsor:

Hospital General Universitario de Valencia

Conditions:

STEMI - ST Elevation Myocardial Infarction

Multivessel Coronary Artery Disease

Eligibility:

All Genders

18-90 years

Phase:

NA

Brief Summary

Patients with STEMI and multivessel disease in whom the culprit lesion has been successfully revascularized during prmimary PCI, will be randomized to in-hospital or after-discharge complete revascula...

Detailed Description

STEMI patients with mutivessel disease are, after successful primary angioplasty, randomized 1:1 ratio to either in-hospital complete revascularization or after-discharge complete revascularization st...

Eligibility Criteria

Inclusion

  • Acute onset of chest pain \<12 hours duration.
  • ST-segment elevation ≥ 0.1 millivolt in ≥ 2 contiguous leads, signs of a true posterior infarction or documented newly developed left bundle branch block.
  • Culprit lesion in a major native vessel, with successful primary PCI.
  • Presence of at least one non-culprit lesion more than or equal to 70% of stenosis in a vessel more than 2mm of diameter or more than or equal to 50% stenosis in proximal segments.
  • The patient is able to give written consent for participation in the study.

Exclusion

  • Pregnancy.
  • Significant left main stenosis.
  • Stent thrombosis.
  • Chronic total occlusion.
  • Severe stenosis of non-culprit vessels with distal flow less than TIMI3.
  • Significant non-culprit stenosis no candidate to revascularization.
  • Presence of valvulopathy candidate for cardiac surgery.
  • Cardiogenic shock status at admission.
  • The patient is not able to give written consent for participation in the study.

Key Trial Info

Start Date :

January 20 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 21 2022

Estimated Enrollment :

250 Patients enrolled

Trial Details

Trial ID

NCT04743154

Start Date

January 20 2018

End Date

December 21 2022

Last Update

April 24 2023

Active Locations (1)

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Hospital General Universitario de Valencia

Valencia, Spain