Status:
COMPLETED
Effect of Topical Anesthesia on Hemodynamics During the Induction Period in Patients Undergo Cardiac Surgery.
Lead Sponsor:
Qianfoshan Hospital
Conditions:
Coronary Artery Disease
Valvular Heart Disease
Eligibility:
All Genders
18-85 years
Phase:
NA
Brief Summary
The aim of the induction is to decrease stress response of endotracheal intubation. It is also important to keep hemodynamics stable during and after the induction period. Previous studies have shown ...
Detailed Description
The routine anesthesia induction strategy for cardiac surgery is to decrease stress response during endotracheal intubation by using large doses of opioids. However, high doses of opioids often leads ...
Eligibility Criteria
Inclusion
- Patients scheduled to accept elective /major cardiac surgery;
- Patients older than 18 years and younger than 85 years;
- Patients of The American Society of Anesthesiologists ( ASA )Ⅱ - Ⅳ level grade;
- Patients signed the informed consent form for the clinical study;
Exclusion
- Patients cannot cooperate to topical anesthesia;
- Patients with a left cardiac assist device prior to surgery;
- Patients with aortic dissection;
- Patients with Intra Aortic Balloon Pump (IABP) prior to surgery;
- Patients treated with Extracorporeal Membrane Oxygenation (ECMO) prior to surgery;
- Patients with difficult airway;
- Patients with high sensitivity and hypersensitivity to lidocaine and tetracaine;
- Patients with atrioventricular block;
- Hemoglobin(Hb)\<80g/L；
- Patients who have participated in other clinical studies during the last 3 months;
Key Trial Info
Start Date :
March 5 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 27 2022
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT04744480
Start Date
March 5 2021
End Date
April 27 2022
Last Update
June 2 2022
Active Locations (1)
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1
Meng-Lv
Jinan, Shandong, China, 250000