Status:

COMPLETED

Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia

Lead Sponsor:

Hospital San Carlos, Madrid

Conditions:

Hyponatremia

Hypovolemia

Eligibility:

All Genders

18+ years

Brief Summary

Retrospective study that analyzes the changes in serum creatinine as a tool to correctly classify the volemic status volemic status (euvolemia vs hypovolemia) of the patients with hyponatremia.

Detailed Description

This study evaluates the usefulness of the changes in serum creatinine in differentiating between euvolemia and hypovolemia in hyponatremic patients. Changes in serum creatinine were retrospectively a...

Eligibility Criteria

Inclusion

  • Patients with hypovolemic hyponatremia secondary to any cause
  • Patients with euvolemic hyponatremia caused by Syndrome of inappropriate antidiuresis
  • Complete clinical volemia assessment during hyponatremia.
  • Presence of serum creatinine measured in eunatremia as well as in hyponatremic episodes.

Exclusion

  • Pregnants.
  • Patients with a prior history of diabetes, advanced chronic kidney disease (glomerular filtrate rate below 30 ml/min), cirrhosis, or heart failure were excluded.
  • Patients with hypervolemic hyponatremia.

Key Trial Info

Start Date :

July 30 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 30 2020

Estimated Enrollment :

122 Patients enrolled

Trial Details

Trial ID

NCT04744987

Start Date

July 30 2019

End Date

October 30 2020

Last Update

August 3 2022

Active Locations (1)

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Servicio de Endocrinología y Nutrición. Hospital Clínico San Carlos

Madrid, Spain, 28040